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KINNEY GENE G.

Date Filed : Feb 23, 2018

X0306 4 2018-02-21 0 0001559053 Prothena Corp plc PRTA 0001564380 Kinney Gene G. C/O PROTHENA BIOSCIENCES INC 331 OYSTER POINT BOULEVARD SOUTH SAN FRANCISCO CA 94080 1 1 0 0 President and CEO Ordinary Shares, par value $0.01 per share 2793 D Stock Option (right to buy) 33.10 2018-02-21 4 A 0 187000 0.00 A 2028-02-21 Ordinary Shares 187000 187000 D The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 21, 2019 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date. /s/ A.W. Homan, as Attorney-in-Fact for Gene G. Kinney 2018-02-23
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