Synlogic enters research collaboration with Roche for development of Novel Therapy to treat InflammatoryBowel disease

Cambridge, Mass. (PR Newswire) June 17, 2021 – Synlogic, Inc. (Nasdaq: SYBX), a clinical stagecompany bringing the transformative potential of synthetic biology to medicine, announced today that it has entered into a research collaboration agreement with Roche for the discovery of a novel Synthetic Biotic™ medicine for the treatment of inflammatory bowel disease (IBD). Under the terms of the agreement, Synlogic and Roche will collaborate to develop a Synthetic Biotic medicine addressing anundisclosed novel target in IBD.

“Our mission is to develop Synthetic Biotic medicines that benefit patients in meaningful ways,” said DavidHava, Ph.D., Synlogic’s Chief Scientific Officer. “We are excited to expand our efforts in inflammation, working to address the unmet needs of patients with inflammatory bowel disease.”

“We are excited to work with Synlogic and explore the potential of a new modality for the treatment of IBD,” said James Sabry, Global Head,Roche Pharma Partnering. “Synlogic and Roche share a commitment to advancing innovative science and delivering transformative medicines to patients living with inflammatory disease.”

At the conclusion of the research period, Roche will have the exclusive option to enter a licensing and collaboration agreement for further development andcommercialization of the program.